Protein-protein conjugate nanoparticles for malaria antigen delivery and enhanced immunogenicity
نویسندگان
چکیده
منابع مشابه
Protein-protein conjugate nanoparticles for malaria antigen delivery and enhanced immunogenicity
Chemical conjugation of polysaccharide to carrier proteins has been a successful strategy to generate potent vaccines against bacterial pathogens. We developed a similar approach for poorly immunogenic malaria protein antigens. Our lead candidates in clinical trials are the malaria transmission blocking vaccine antigens, Pfs25 and Pfs230D1, individually conjugated to the carrier protein Exoprot...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2017
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0190312